What is a potential consequence of ineffective drug metabolism in clients with liver disease?

Disable ads (and more) with a premium pass for a one time $4.99 payment

Prepare for the Canadian Practical Nurse Registration Examination. Explore flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam!

Ineffective drug metabolism in clients with liver disease can lead to higher levels of the drug remaining in the body. The liver plays a crucial role in metabolizing and clearing medications; when liver function is compromised, the ability to process and eliminate drugs diminishes. As a result, drugs can accumulate in the bloodstream, increasing the risk of toxicity and adverse effects.

In clients with liver disease, the reduced enzymatic activity of the liver can lead to slower metabolism of drugs that are usually eliminated efficiently. Consequently, the concentration of the active drug can remain elevated for an extended period, which may exacerbate side effects and increase the risk of overdose. Furthermore, the accumulation of drugs can lead to an unpredictable and potentially dangerous pharmacokinetic profile in these patients, warranting careful monitoring and dosage adjustments.

The other options do not accurately represent the implications of ineffective drug metabolism in this context. Increased absorption of nutrients and faster drug clearance are not typical consequences of liver dysfunction, and reduced drug efficacy is more related to factors like tolerance or drug interactions rather than primary liver metabolism issues.

Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy